Under-eye skin is notoriously thin, delicate, and prone to darkness, hollowing, and fine lines. At Refine Aesthetics, we’re always looking for smart, clean, science-backed solutions, and that’s where PDGF comes in. PDGF stands for Platelet-Derived Growth Factor: a powerhouse protein that rebuilds and rejuvenates from within.
What is PDGF and How We Use It
PDGF is a healing messenger. When your body needs repairs (like skin, tissue, or even bone) PDGF signals fibroblasts to create collagen and elastin, and it encourages new blood vessels to form. Here at Refine, we go beyond PRP (your own blood products). We use a lab-made, pharmaceutical-grade PDGF blend that’s consistent, sterile, and potent. You won’t need a blood draw and the results won’t vary based on health, stress, or hydration. Interested in learning more about the PDGF product that we use? Look here.
How PDGF Targets Under-Eye Concerns
1. Boosting Collagen & Elastin
PDGF activates fibroblasts, thickening the under-eye skin to reduce crepiness and fine lines.
2. Improving Circulation
By stimulating new capillaries, PDGF brings more oxygen to the skin and lightens dark circles.
3. Speeding Repair & Hydration
When paired with microneedling or laser sessions, PDGF accelerates healing and enhances hydration, delivering a smoother, firmer outcome.
If you want to dive deeper, check out our PDGF page to see how growth-factor therapies are part of our toolkit.
Why PDGF over Fillers or PRP for Under-Eyes
- Fillers add volume instantly but can sometimes shift or feel unnatural, especially under the eye where the tissue is very thin.
- PRP uses your blood—effective, but inconsistent depending on your physiology.
- Lab-grade PDGF gives predictable, high-potency results every time. No blood draw. No surprises. Essentially, PDGF is the upgrade that every PRP and Filler patient has been waiting for.
There are occasions where PDGF can be used in combination with fillers for the best results. Just like combining a biostimulator with other filler products can yield beautiful outcomes, using two modalities under the eyes can be extremely effective in giving you the most natural, rejuvenated result. This all depends on your desired outcome, treatment history, anatomy, and skin quality of course! ALWAYS consult with your trusted injector before making assumptions on the best plan of care.
What Your PDGF Experience Looks Like:
- Clean and prep the under-eye area.
- Inject PDGF under the eyes.
- Expect minimal swelling or redness for 24–48 hours.
- See early improvements within a week. Full results—firmer skin, smoother texture, less shadowing—by week 4 to 6.
- Maintain with touch-up sessions every 6–12 months.
This approach combines science with strategy. For even better outcomes, pair PDGF with our laser or microneedling services. Our blog explains why combining treatments creates more impressive rejuvenation; check out Microneedling vs Laser for details.
Safety You Can Trust:
PDGF has safe, well-documented use in regenerative medicine including wound healing and orthopedic repair. In our med spa setting, we use a pure, minimal formula—water, hyaluronic acid, and the growth factor. Side effects are rare and mild, typically limited to temporary redness.
Is It Right For You?
PDGF is perfect if you’re:
- Dealing with fine under-eye lines, thin skin, or dark circles
- Looking for natural results without filler
- Wanting consistent, science-based treatments rather than blood-derived variability
In Summary
PDGF supports your under-eyes by:
- Rebuilding collagen and elastin
- Improving circulation to reduce shadows
- Enhancing healing and hydration
- Offering clean and controlled results
At Refine Aesthetics, we believe in thoughtful, precision-driven care. PDGF is the smart, inside-out solution for strong, radiant under-eye skin. If you’re ready to move beyond fillers and unpredictable blood-based treatments, let’s talk PDGF. Schedule your consultation and let me guide you through a plan tailored to your eyes—and your energy for excellence.
Looking forward to helping you look and feel your best,
